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A different way to do biosecurity : Two thoughts
Environmental Bio-surveillance A key consensus ported over from the Life Sciences into biosecurity is that of accurate testing. Which is important. This consensus is atleast incomplete.The focus on making tests faster, more sensitive, higher fidelity has lost the question whether accuracy is the right constraint. Perfect information about 0.01% of samples (or environment) is still — read more
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Math in the Park
Organized a random Math in the Park in Patterson Park a couple of weeks ago (8 people were six more than I expected!). And no, I can’t solve my year’s JEE Math paper anymore! — read more
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MagnaSlide (Union Lung 2023, Paris)
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The missing revolution
I recently proposed an open source project. Others might useful. Question 1Describe the problem you expect your residency to focus on and your proposed solution or direction for identifying a solution. Aim for a level of explanation that a smart college freshman could understand.–One reason Bonolo and I started Drizzle Health was because we couldn’t — read more
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Two startup thoughts about romantic relationships
Romantic relationships seem pretty similar to startups, imo. There’s a journey of one’s ‘becoming’ and in that spiritual sense, relationships can represent the Earth in a cold universe. A place of life and nourishment, that fuels, nourishes and pushes you in a pretty symbiotic way. (I say symbiotic because I can’t rule out that the — read more
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Why fast food E. coli outbreaks are (currently) inevitable
(Originally appeared on this twitter thread) As population consumption needs rise, food production and processing is trying to keep up. Food recalls increased by about 40% in 2024. But why are E. coli outbreaks at McDonald’s and Chipotle common? There’s lots of answers including the complexity of supply chains, but for consumer facing fast food, — read more
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USAID is gone. What about the state of the art diagnostics machines left behind?
Originally published on the Drizzle Health Substack *written with inputs from Iniya and Bonolo. Perfect Test ≠ Perfect Solution The discovery of DNA polymerases is said to be the equivalent of discovering fire in the world of diagnostics. When Kary Mullis invented PCR in 1985, it wasn’t just another laboratory technique – it was a — read more
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TB in India: We’re not in the molecular age. Yet.
TLDR; 70% of TB testing in India is done using a test as good as a coin-toss. If we’re really serious about helping the millions of people that get TB, and will get TB in India every year, we need to accept our hubris, and use the advantage India already has. Not just the promise — read more
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Large Scale Diagnostics
TLDR; Through the development of selective sample concentration for Tuberculosis Diagnostics, a key learning for us from the technology standpoint was the performance difference in being able to handle small and large samples. Most In-vitro Diagnostics (IVDs) are designed for small samples. Think about it. A PCR is $20 per test. But it is also — read more
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On Love (and morality)
This community essay was originally written for and published on Interintellect I’ve often thought of morality as an artifact of the prisoner’s dilemma. In the past, the best outcome for many situations in a community was achieved via a compromise and what was best for the group. Morality, thus, was shorthand for navigating everyday situations. Don’t — read more
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The Piano Lab 